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However, many of these therapies create chronic conditions that adversely impact breast cancer survivors’ bones and vagina.” Lasofoxifene is being investigated for the treatment of metastatic breast cancer and, if found effective, will have the potential to provide women with an improved alternative to existing endocrine treatments. “The results of this physician survey interview skills online course highlight the unmet medical needs women have during and after endocrine treatment of their breast cancer,” said Dr. Plourde. “Anti-estrogens have been the cornerstone of ER+ breast cancer for decades, yet physicians have underappreciated the impact such therapy has on quality of life. Oral lasofoxifene is a novel investigational agent with a strong anti-estrogen effect on breast. It also has beneficial estrogenic effects on the vagina and bone that helps mitigate bone loss and symptoms related to vaginal atrophy.” About Sermonix Sermonix Pharmaceuticals LLC is a specialty pharmaceutical company with a targeted focus towards bringing female-specific oncology products through proof of concept, preclinical and clinical development with a clear regulatory pathway in place. The company was founded in 2014 by David Portman, MD, a leading clinical researcher and expert in women’s health, menopause and selective estrogen receptor modulator (SERM) therapy. Sermonix has as its lead product oral lasofoxifene, with exclusive licensing rights for the U.S. and Japan obtained from Ligand Pharmaceuticals, Inc. The Sermonix internal management team, led by Dr.
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